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Michael A Jakupec Selected Research

Teratocarcinoma

7/2021Tridentate 3-Substituted Naphthoquinone Ruthenium Arene Complexes: Synthesis, Characterization, Aqueous Behavior, and Theoretical and Biological Studies.
3/2020Tetra-(p-tolyl)antimony(III)-Containing Heteropolytungstates, [{(p-tolyl)SbIII}4(A-α-XW9O34)2]n- (X = P, As, or Ge): Synthesis, Structure, and Study of Antibacterial and Antitumor Activity.
1/2017Impact of the equatorial coordination sphere on the rate of reduction, lipophilicity and cytotoxic activity of platinum(IV) complexes.
12/2015Tetracarboxylatoplatinum(IV) complexes featuring monodentate leaving groups - A rational approach toward exploiting the platinum(IV) prodrug strategy.

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Michael A Jakupec Research Topics

Disease

76Neoplasms (Cancer)
01/2022 - 07/2002
25Carcinoma (Carcinomatosis)
03/2020 - 01/2005
8Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2020 - 08/2008
5Colorectal Neoplasms (Colorectal Cancer)
08/2021 - 01/2004
5Colonic Neoplasms (Colon Cancer)
10/2019 - 01/2004
4Teratocarcinoma
07/2021 - 12/2015
3Neoplasm Metastasis (Metastasis)
12/2021 - 08/2015
3Ovarian Neoplasms (Ovarian Cancer)
07/2015 - 01/2004
2Leukemia L1210
01/2017 - 01/2014
1Leukemia
12/2021
1Hypersensitivity (Allergy)
12/2021
1Breast Neoplasms (Breast Cancer)
01/2020
1Hypoxia (Hypoxemia)
04/2016
1Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2016
1Malaria
12/2009

Drug/Important Bio-Agent (IBA)

20RutheniumIBA
01/2022 - 08/2005
19Cisplatin (Platino)FDA LinkGeneric
03/2018 - 01/2005
18PlatinumIBA
08/2021 - 01/2004
16LigandsIBA
01/2020 - 01/2004
13Pharmaceutical PreparationsIBA
12/2021 - 05/2006
10MetalsIBA
01/2022 - 01/2004
10Oxaliplatin (Eloxatin)FDA LinkGeneric
08/2021 - 01/2004
8OsmiumIBA
01/2022 - 08/2008
8GalliumIBA
08/2015 - 07/2002
5Biological ProductsIBA
01/2022 - 12/2009
5DNA (Deoxyribonucleic Acid)IBA
11/2020 - 08/2010
5IndazolesIBA
01/2019 - 05/2007
5indazolium trans- (tetrachlorobis(1H- indazole)ruthenate (III))IBA
07/2014 - 08/2005
54-cymene (p-cymene)IBA
07/2013 - 05/2009
4Proteins (Proteins, Gene)FDA Link
12/2019 - 12/2009
4diphenyl (biphenyl)IBA
03/2013 - 10/2008
3Antineoplastic Agents (Antineoplastics)IBA
12/2021 - 11/2006
3KP 1339IBA
08/2021 - 08/2015
3SodiumIBA
01/2019 - 06/2015
3ProdrugsIBA
09/2017 - 07/2015
3Coordination ComplexesIBA
08/2016 - 01/2009
3CationsIBA
11/2009 - 01/2004
2RhodiumIBA
01/2022 - 01/2020
2IridiumIBA
01/2022 - 01/2020
23-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA
03/2014 - 01/2010
2paulloneIBA
11/2013 - 09/2012
2CopperIBA
11/2013 - 09/2012
2QuinolinesIBA
09/2013 - 08/2010
2CymenesIBA
03/2013 - 11/2009
2Transferrin (beta 2 Transferrin)IBA
02/2013 - 11/2006
2BenzazepinesIBA
12/2011 - 08/2010
2BromidesIBA
10/2009 - 12/2008
2Ruthenium CompoundsIBA
08/2008 - 06/2007
2tris(8-quinolinolato)gallium (III)IBA
11/2006 - 01/2004
2IronIBA
01/2004 - 01/2004
2gallium nitrateFDA Link
01/2004 - 01/2004
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
01/2004 - 01/2004
2Transferrin Receptors (Transferrin Receptor)IBA
01/2004 - 01/2004
1ApatitesIBA
12/2021
1Diphosphonates (Bisphosphonates)IBA
12/2021
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2021
1polyanionsIBA
03/2020
1EnzymesIBA
01/2020
13-hydroxy-2-methyl-4H-pyran-4-thioneIBA
01/2020
1Adenosine Triphosphate (ATP)IBA
01/2019
1CalreticulinIBA
01/2019
1PlectinIBA
01/2017
1SolutionsIBA
11/2016
1Platinum Compounds (Compounds, Platinum)IBA
04/2016
1Type II DNA Topoisomerases (Topoisomerase II)IBA
01/2016
1FlavonoidsIBA
01/2016
1diacetyldichlorofluoresceinIBA
01/2016
1NKP-1339IBA
01/2016
1LanthanumIBA
08/2015
1acetyl acetonate (acetylacetonate)IBA
06/2015
1VanadiumIBA
06/2015
1Vanadates (Orthovanadate)IBA
06/2015
1phosphoramidic acidIBA
07/2014
1Activating Transcription FactorsIBA
03/2014
11,2-cyclohexanediamine (dach)IBA
01/2014
1TEMPOIBA
11/2013
1Peptides (Polypeptides)IBA
07/2013
1CarbonatesIBA
02/2013
1Glutathione (Reduced Glutathione)IBA
02/2013
1BuffersIBA
02/2013
1CarbohydratesIBA
01/2013
13-hydroxyflavoneIBA
12/2012
1ChloridesIBA
11/2012
1OximesIBA
10/2012
1EthersIBA
10/2012
1Choline (Choline Chloride)IBA
10/2012
1Free RadicalsIBA
09/2012
14-amino-TEMPO (A-TEMPO)IBA
09/2012
1Human Serum AlbuminFDA LinkGeneric
12/2011
1PyridinesIBA
12/2011
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
12/2011
1Cyclin-Dependent Kinases (cdk Proteins)IBA
08/2010
1Blood Proteins (Serum Proteins)IBA
12/2009
1NucleotidesIBA
12/2009

Therapy/Procedure

6Therapeutics
12/2021 - 01/2004
4Drug Therapy (Chemotherapy)
03/2018 - 01/2004
2Aftercare (After-Treatment)
01/2017 - 04/2015
1Laser Therapy (Surgery, Laser)
11/2020
1Oral Administration
01/2017
1Transplantation
08/2012